SCHEMBL466476

SCHEMBL466476

CCCC(C(F)(F)F)S(=O)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 3/20 0.36
HDAC2 Q92769 3/20 0.36
CHRM1 P11229 1/20 0.36
AKR1A1 P14550 1/20 0.36
CHRM3 P20309 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36
DRD3 P35462 1/20 0.36
SLC6A3 Q01959 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP3A4 P08684 2/20 0.34
TSHR P16473 2/20 0.34
NFKB1 P19838 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
TP53 P04637 1/20 0.33
HDAC7 Q8WUI4 3/20 0.32
HDAC8 Q9BY41 3/20 0.32
HDAC6 Q9UBN7 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4344566 0.87 TP53 (0.39) TP53EPHX1FDPS
SCHEMBL28887913 0.85 TP53 (0.47) TP53EPHX1FDPS
SCHEMBL4759458 0.84 TP53 (0.46) TP53EPHX1FDPS
SCHEMBL3873600 0.84 TP53 (0.46) TP53EPHX1FDPS
SCHEMBL8638153 0.81 CA1 (0.31)
SCHEMBL3873895 0.81
1,4-Butanediol SCHEMBL576085 0.81 TP53 (0.43) TSHRTP53EPHX1
SCHEMBL575574 0.81 TP53 (0.47) TP53EPHX1
1,3-Propanediol SCHEMBL575643 0.81 TP53 (0.43) TSHRTP53EPHX1
SCHEMBL30856470 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294135-B1 FLAME RETARDANT, OPTICALLY CLEAR THERMOPLASTIC MOLDING COMPOSITION COVESTRO LLC (US) 2017-07-26 EP claimed
EP-2673318-B1 FLAME RETARDANT, THERMOPLASTIC POLYCARBONATE MOLDING COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2017-07-05 EP claimed
EP-2480608-B1 FLAME RETARDANT, OPTICALLY CLEAR THERMOPLASTIC MOLDING COMPOSITION COVESTRO LLC (US) 2017-05-24 EP claimed
EP-2176334-B1 FLAME RESISTANT POLYCARBONATE COMPOSITION COVESTRO LLC (US) 2016-12-14 EP claimed
EP-1497374-B1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GEN ELECTRIC (US) 2008-08-13 EP claimed
US-7244778-B2 Filler reinforced polyether imide resin composition and molded article thereof GENERAL ELECTRIC COMPANY (US) 2007-07-17 US claimed
US-20050131105-A1 Filler reinforced polyether imide resin composition and molded article thereof SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2005-06-16 US claimed
EP-1448712-A1 FLAME RETARDANT RESINOUS COMPOSITIONS AND METHOD General Electric Company, (a New York Corporation) (US) 2004-08-25 EP claimed
US-6613824-B2 Composition comprising aromatic carbonate, polymer derived from vinyl aromatic, unsaturated nitrile or (meth)acrylate ester monomers, rubber modified graft copolymer, organic phosphorus species, antidrip agent, perfluoroalkanesulfonate GENERAL ELECTRIC COMPANY 2003-09-02 US claimed
US-20030109650-A1 Flame retardant resinous compositions and method GENERAL ELECTRIC COMPANY 2003-06-12 US claimed
WO-2003042303-A1 FLAME RETARDANT RESINOUS COMPOSITIONS AND METHOD GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) 2003-05-22 WO claimed
US-12544961-B2 Thermosetting composition for injection molding, method for producing molded article using the same, and cured product IDEMITSU KOSAN CO., LTD. (JP) 2026-02-10 US disclosed
US-12528915-B2 Polycarbonate resin composition IDEMITSU KOSAN CO.,LTD. (JP) 2026-01-20 US disclosed
US-20250354010-A1 MOLDED BODY INCLUDING POLYCARBONATE-BASED RESIN COMPOSITION IDEMITSU KOSAN CO.,LTD. (JP) 2025-11-20 US disclosed
EP-4650400-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE FORMED OF SAME Teijin Limited (JP) 2025-11-19 EP disclosed
EP-0625547-B1 Flame retardative polycarbonate resin composition IDEMITSU PETROCHEMICAL CO (JP) 1998-10-14 EP disclosed
US-5449710-A Blends with metal salts of perfluoroalkanesulfonic acid and organopolysiloxane with optional fillers to prevent dripping IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-09-12 US disclosed
EP-0625547-A1 Flame retardative polycarbonate resin composition IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1994-11-23 EP disclosed
US-RE33032-E Polycarbonate films of low flammability and improved stress crack resistance BAYER AKTIENGESELLSCHAFT (DE) 1989-08-22 US disclosed
US-4214062-A INCORPORATING NH4, ALKALI METAL OR ALKALINE EARTH METAL SALT OF A PERHALOGENOALKANESULFONIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1980-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544961-B2 Thermosetting composition for injection molding, method for producing molded article using the same, and cured product MAT2B, MAT1A, MMAB HDAC1 3089/4885HDAC2 3397/4885CHRM1 3216/4885
US-12528915-B2 Polycarbonate resin composition PSMB2, PSMA1, PSMB1 HDAC1 1278/4885HDAC2 1809/4885CHRM1 3931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.