Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 8/20 | 0.55 |
| ▸ | CA9 | Q16790 | 6/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | STS | P08842 | 6/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666101 | 0.85 | STS (0.58) | CA2CA9CA1STSCYP19A1 | |
| SCHEMBL4009763 | 0.80 | MMP3 (0.82) | MMP3 | |
| SCHEMBL4001097 | 0.80 | MMP3 (0.82) | MMP3 | |
| SCHEMBL4667205 | 0.78 | CA2 (0.63) | CA2CA9CA1STSCYP19A1 | |
| SCHEMBL30504282 | 0.78 | MMP3 (0.79) | MMP3 | |
| SCHEMBL4665452 | 0.77 | STS (0.68) | CA2CA9CA1STSCYP19A1 | |
| SCHEMBL338712 | 0.75 | MMP3 (0.73) | MMP3 | |
| SCHEMBL4006124 | 0.75 | MMP3 (0.72) | MMP3 | |
| SCHEMBL4668705 | 0.74 | CA2 (0.54) | CA2CA9CA1STSCYP19A1 | |
| SCHEMBL4667165 | 0.73 | CA2 (0.66) | CA2CA9CA1STSCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |