Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 1.00 |
| ▸ | CA2 | P00918 | 11/20 | 0.89 |
| ▸ | CA9 | Q16790 | 11/20 | 0.89 |
| ▸ | CA1 | P00915 | 10/20 | 0.89 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451383 | 0.94 | CA2 (1.00) | KIF11CA2CA9CA1KMT2A | |
| SCHEMBL4043267 | 0.92 | CA2 (0.96) | KIF11CA2CA9CA1KMT2A | |
| SCHEMBL26549580 | 0.83 | KIF11 (0.71) | KIF11CA2CA9CA1 | |
| SCHEMBL28390592 | 0.80 | CA2 (0.73) | KIF11CA2CA9CA1KMT2A | |
| SCHEMBL23557819 | 0.77 | PTGS2 (0.72) | KIF11CA2CA9CA1STS | |
| SCHEMBL4668665 | 0.77 | STS (0.68) | KIF11CA2CA9CA1STS | |
| SCHEMBL6800282 | 0.77 | CA1 (0.67) | KIF11CA2CA9CA1KMT2A | |
| SCHEMBL4666147 | 0.76 | CA2 (0.70) | KIF11CA2CA9CA1STS | |
| SCHEMBL408478 | 0.76 | CA1 (0.68) | KIF11CA2CA9CA1KMT2A | |
| SCHEMBL16140137 | 0.76 | CA2 (0.68) | KIF11CA2CA9CA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |