Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.62 |
| ▸ | CA9 | Q16790 | 12/20 | 0.62 |
| ▸ | CA1 | P00915 | 11/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 6/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665426 | 0.79 | CA2 (0.62) | CA2CA9CA1ALDH1A1CA12 | |
| SCHEMBL4668685 | 0.79 | CA2 (0.62) | CA2CA9CA1CA12STS | |
| SCHEMBL7263619 | 0.77 | CA2 (1.00) | CA2CA9CA1CA12STS | |
| SCHEMBL4668710 | 0.77 | CA2 (0.62) | CA2CA9CA1CA12 | |
| SCHEMBL4665386 | 0.76 | CA2 (0.88) | CA2CA9CA1CA12STS | |
| SCHEMBL4777296 | 0.76 | KIF11 (0.59) | CA2CA9CA1CA12STS | |
| SCHEMBL4667170 | 0.76 | CA2 (0.58) | CA2CA9CA1CA12STS | |
| SCHEMBL4667728 | 0.76 | STS (0.68) | CA2CA9CA1CA12STS | |
| SCHEMBL7615464 | 0.75 | ALDH1A1 (0.62) | ALDH1A1MAPK1 | |
| SCHEMBL4667326 | 0.74 | ALDH1A1 (0.57) | CA2CA9CA1ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |