Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3089100 | 0.89 | CUL4A (0.38) | CUL4AHSD17B2HSD17B1NOTUMPIM1 | |
| SCHEMBL16372082 | 0.84 | HSD17B2 (0.47) | CUL4AHSD17B2HSD17B1NOTUMPDE3B | |
| SCHEMBL16612698 | 0.78 | CUL4A (0.40) | CUL4AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4668796 | 0.77 | SOS1 (0.49) | HSD17B2HSD17B1NOTUMSOS1KDM4E | |
| SCHEMBL16372098 | 0.76 | CUL4A (0.39) | CUL4AHSD17B2HSD17B1KDM4EHSD17B10 | |
| SCHEMBL16372027 | 0.74 | HSD17B1 (0.33) | HSD17B2HSD17B1PDE3BPDE3AKDM4E | |
| SCHEMBL3088157 | 0.72 | HSD17B2 (0.48) | HSD17B2HSD17B1 | |
| SCHEMBL4867699 | 0.70 | ENPP3 (0.39) | HSD17B2HSD17B1PIM1PDE3BPDE3A | |
| SCHEMBL22867444 | 0.69 | KDM4E (0.43) | HSD17B2HSD17B1NOTUMKDM4EHSD17B10 | |
| SCHEMBL19438437 | 0.69 | CYP2C19 (0.46) | CUL4ANOTUMKDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144879-B1 | PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-1987717-A1 | Pyridon carboxamides, agents containing these but not impacting useful plants and method for their manufacture and application | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |