Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665653 | 0.89 | CUL4A (0.39) | CUL4AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16372098 | 0.85 | CUL4A (0.39) | CUL4AKDM4EHPGDHSD17B10JAK2 | |
| SCHEMBL4906582 | 0.78 | SOS1 (0.44) | NOTUMKDM4EALDH1A1GAAMAPT | |
| SCHEMBL16372082 | 0.76 | HSD17B2 (0.47) | CUL4ANOTUMKDM4EHPGDHSD17B10 | |
| SCHEMBL16612698 | 0.76 | CUL4A (0.40) | CUL4AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4667450 | 0.73 | HSD17B2 (0.38) | CUL4AKDM4EHPGDHSD17B10JAK2 | |
| SCHEMBL16372027 | 0.72 | HSD17B1 (0.33) | KDM4EHPGDHSD17B10HSD17B1HSD17B2 | |
| SCHEMBL16371315 | 0.69 | DAO (0.30) | — | |
| SCHEMBL16612938 | 0.69 | HSD17B2 (0.37) | CUL4AKDM4EHPGDHSD17B10JAK2 | |
| SCHEMBL3088157 | 0.67 | HSD17B2 (0.48) | HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144879-B1 | PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2144879-A2 | PYRIDONECARBOXAMIDES CROP PROTECTION AGENTS CONTAINING THE SAME METHOD FOR PRODUCTION AND USE THEREOF | Bayer CropScience AG (DE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008131860-A2 | PYRIDONECARBOXAMIDES CROP PROTECTION AGENTS CONTAINING THE SAME METHOD FOR PRODUCTION AND USE THEREOF | BAYER CROPSCIENCE AG (DE) | 2008-11-06 | — | — | WO | disclosed |