Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664260 | 0.83 | ALDH1A1 (0.45) | NR1H2NR1H3MAPTALDH1A1KDM4E | |
| SCHEMBL4663824 | 0.83 | S1PR1 (0.48) | NR1H2NR1H3ALDH1A1KDM4EPOLB | |
| SCHEMBL20171826 | 0.79 | ALDH1A1 (0.44) | NR1H2NR1H3ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL11133767 | 0.79 | MAPT (0.65) | NR1H2NR1H3MAPTALDH1A1KDM4E | |
| SCHEMBL4870098 | 0.78 | EGFR (0.49) | NR1H2NR1H3MAPTALDH1A1CNR2 | |
| SCHEMBL11000207 | 0.78 | ALDH1A1 (0.55) | NR1H2NR1H3MAPTALDH1A1KDM4E | |
| SCHEMBL15592515 | 0.77 | NOS1 (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL22589015 | 0.77 | S1PR1 (0.46) | NR1H2NR1H3ALDH1A1DRD2OPRM1 | |
| SCHEMBL5284253 | 0.77 | ALDH1A1 (0.50) | NR1H2NR1H3MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3373755 | 0.77 | EGFR (0.47) | NR1H2NR1H3MAPTALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080122428-A1 | Optimized Determination of Voltage Changes Using a Voltage-Sensitive Dye | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNGDER WISSENSCHAFTEN E. V. (DE) | 2008-05-29 | — | — | US | disclosed |
| EP-1644722-A1 | OPTIMIZED DETERMINATION OF VOLTAGE CHANGES USING A VOLTAGE-SENSITIVE DYE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005001448-A1 | OPTIMIZED DETERMINATION OF VOLTAGE CHANGES USING A VOLTAGE-SENSITIVE DYE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080122428-A1 | Optimized Determination of Voltage Changes Using a Voltage-Sensitive Dye | HVCN1, CACNG5, CACNB4 | NR1H2 4042/4885NR1H3 3858/4885MAPT 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.