Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983460 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL2983173 | 0.78 | SMN1; SMN2 (0.54) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL2990832 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL2990833 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL2992222 | 0.72 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL2986118 | 0.71 | ACLY (0.53) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL13245973 | 0.71 | GHSR (0.54) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL4730290 | 0.71 | LMNA (0.71) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL2991778 | 0.70 | GHSR (0.54) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL4763638 | 0.70 | ALDH1A1 (0.45) | ALDH1A1KDM4EKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007716-A1 | ARYL AND HETEROARYL SULPHONAMIDES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118852-A1 | ARYL AND HETEROARYL SULPHONAMIDES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2007-10-25 | — | — | WO | disclosed |