Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 10/20 | 0.46 |
| ▸ | FABP3 | P05413 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668225 | 0.91 | ADORA1 (0.44) | ADORA1FABP3FABP4ADORA2AADORA2B | |
| SCHEMBL4633959 | 0.89 | ADORA1 (0.44) | ADORA1FABP3FABP4ADORA2AADORA2B | |
| SCHEMBL14600188 | 0.87 | ADORA1 (0.44) | ADORA1ADORA2AADORA2BKDM4C | |
| SCHEMBL4634753 | 0.86 | ADORA1 (0.43) | ADORA1FABP3FABP4ADORA2AADORA2B | |
| SCHEMBL4667046 | 0.80 | ADORA1 (0.52) | ADORA1FABP3FABP4ADORA2BKDM4C | |
| SCHEMBL4668860 | 0.78 | KCNMA1 (0.38) | KDM4E | |
| SCHEMBL4668016 | 0.77 | ADORA1 (0.53) | ADORA1KDM4C | |
| SCHEMBL14600443 | 0.73 | MAPK14 (0.53) | — | |
| SCHEMBL4667036 | 0.73 | ADORA1 (0.46) | ADORA1FABP3FABP4ADORA2AADORA2B | |
| SCHEMBL14600712 | 0.72 | ADORA1 (0.50) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |