Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.71 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.61 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL6849688 | 0.93 | OR51E2 (0.75) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL14977810 | 0.90 | OR51E2 (0.79) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL6929736 | 0.90 | OR51E2 (0.79) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL353224 | 0.90 | OR51E2 (0.79) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL14977562 | 0.90 | OR51E2 (0.79) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL4655461 | 0.90 | OR51E2 (0.88) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL3356160 | 0.90 | — | — | |
| 2-Pyrrolidone SCHEMBL3729403 | 0.88 | OR51E2 (0.68) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL28310048 | 0.88 | OR51E2 (0.68) | OR51E2CRBNFKBP5KDM4EGAA | |
| 2-Pyrrolidone SCHEMBL22749298 | 0.88 | OR51E2 (0.75) | OR51E2CRBNFKBP5KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104284951-A | Ink composition, method for preparing the ink composition and use thereof, water-soluble resin and use thereof in ink composition | OCE TECH BV | 2015-01-14 | — | — | CN | disclosed |
| EP-1515755-B1 | Process for the reduction of loss of active substances | ECOLAB INC (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-1515755-A1 | AQUEOUS CONCENTRATE FOR THE DISINFECTION OF SURFACES | Ecolab Inc. (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004000373-A1 | AQUEOUS CONCENTRATE FOR THE DISINFECTION OF SURFACES | ECOLAB INC. (US) | 2003-12-31 | — | — | WO | disclosed |
| CN-1341594-A | Substituted pyrrolidone, thiazolidone or oxazolidone as herbicide | ZENECA LTD (GB) | 2002-03-27 | — | — | CN | disclosed |
| EP-1059977-A2 | RECOVERY OF ORGANIC SOLUTES FROM AQUEOUS SOLUTIONS | Varian, Inc. (US) | 2000-12-20 | — | — | EP | disclosed |
| US-6071410-A | Recovery of organic solutes from aqueous solutions | VARIAN, INC. (US) | 2000-06-06 | — | — | US | disclosed |
| WO-2000029088-A2 | RECOVERY OF ORGANIC SOLUTES FROM AQUEOUS SOLUTIONS | VARIAN, INC. (US) | 2000-05-25 | — | — | WO | disclosed |
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | disclosed |
| EP-0828710-A1 | PROCESS FOR THE PREPARATION OF (THIO-)CARBONIC/CARBAMIC ACID 2-PYRROLIDONYL-3-ESTERS, THIO ESTERS AND AMIDES | ZENECA LIMITED (GB) | 1998-03-18 | — | — | EP | disclosed |
| CN-1153512-A | Substituted pyrrolidones, thiazolidinones or oxazolidinones as herbicides | ZENECA LTD (GB) | 1997-07-02 | — | — | CN | disclosed |
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| US-5591856-A | CHEMICAL INTERMEDIATES, TREATMENT OF ALZHEIMER'S DISEASE | HOECHST ROUSSEL PHARMACEUTICALS INC. (US) | 1997-01-07 | — | — | US | disclosed |
| WO-1996037466-A1 | PROCESS FOR THE PREPARATION OF (THIO-)CARBONIC/CARBAMIC ACID 2-PYRROLIDONYL-3-ESTERS, THIO ESTERS AND AMIDES | ZENECA LIMITED (GB) | 1996-11-28 | — | — | WO | disclosed |
| US-5554750-A | TO RELIEVE MEMORY DYSFUNCTIONS; TREATMENT OF ALZHEMER*S | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1996-09-10 | — | — | US | disclosed |
| EP-0671388-A1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5405845-A | Administering to relieve memory dysfunction; treatment of Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-04-11 | — | — | US | disclosed |
| US-5338739-A | Memory dysfunction relieving compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-08-16 | — | — | US | disclosed |
| US-4416684-A | PYRROLIDONE AND M-UREIDOPHENYL CARBAMATE | STAUFFER CHEMICAL COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| US-3948943-A | THERAPEUTIC, DERMATOLOGICAL, COSMETIC | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-06 | — | — | US | disclosed |