Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13414996 | 0.92 | NPC1 (0.36) | NPC1RAB9AATMSLC6A4MAPT | |
| SCHEMBL9451018 | 0.82 | MEN1 (0.41) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9778649 | 0.82 | PRKDC (0.43) | NPC1RAB9AATM | |
| SCHEMBL19661840 | 0.77 | KCNH2 (0.41) | NPC1SLC6A4MAPTSLC6A2SLC6A3 | |
| SCHEMBL4263862 | 0.77 | NPC1 (0.51) | NPC1RAB9AMAPTMEN1GAA | |
| SCHEMBL3083609 | 0.77 | RAB9A (0.44) | NPC1RAB9AMAPTMEN1GAA | |
| SCHEMBL6236362 | 0.72 | MEN1 (0.36) | NPC1RAB9AMAPTMEN1GAA | |
| SCHEMBL2633867 | 0.72 | MAPK1 (0.47) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL3140395 | 0.72 | MAPT (0.51) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL511959 | 0.72 | KDM1A (0.40) | SLC6A4SLC6A2SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982002-B2 | Sulfoxidation catalysts and methods for their preparation and use | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2018-05-29 | — | — | US | disclosed |
| US-9982002-B2 | Sulfoxidation catalysts and methods for their preparation and use | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2018-05-29 | — | — | US | disclosed |
| US-20160251388-A1 | SULFOXIDATION CATALYSTS AND METHODS FOR THEIR PREPARATION AND USE | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2016-09-01 | — | — | US | disclosed |
| US-20160251388-A1 | SULFOXIDATION CATALYSTS AND METHODS FOR THEIR PREPARATION AND USE | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2016-09-01 | — | — | US | disclosed |
| WO-2015056117-A2 | SULFOXIDATION CATALYSTS AND METHODS FOR THEIR PREPARATION AND USE | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2015-04-23 | — | — | WO | disclosed |
| EP-1638551-B1 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2011-12-21 | — | — | EP | disclosed |
| EP-1638551-A4 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-12-31 | — | — | EP | disclosed |
| US-7060697-B2 | Immunosuppressant compounds and compositions | IRM LLC (BM) | 2006-06-13 | — | — | US | disclosed |
| EP-1638551-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2006-03-29 | — | — | EP | disclosed |
| US-20050014724-A1 | Immunosuppressant compounds and compositions | IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) | 2005-01-20 | — | — | US | disclosed |
| WO-2004103309-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160251388-A1 | SULFOXIDATION CATALYSTS AND METHODS FOR THEIR PREPARATION AND USE | SMOX, TST, STS | NPC1 4870/4885RAB9A 4167/4885ATM 2640/4885 |
| US-20050014724-A1 | Immunosuppressant compounds and compositions | ICOS, EDNRA, NFATC1 | NPC1 2745/4885RAB9A 3413/4885ATM 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.