Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.47 |
| ▸ | CA9 | Q16790 | 9/20 | 0.47 |
| ▸ | CA1 | P00915 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8158755 | 0.83 | HSD17B10 (0.49) | HSD17B10ALDH1A1TDP1KMT2AMAPT | |
| SCHEMBL4667326 | 0.79 | ALDH1A1 (0.57) | CA2CA9CA1ALDH1A1TDP1 | |
| SCHEMBL27571950 | 0.77 | CA2 (0.53) | CA2CA9CA1ALDH1A1TDP1 | |
| SCHEMBL31542121 | 0.75 | MAOB (0.56) | HSD17B10ALDH1A1TDP1KMT2AMAPT | |
| SCHEMBL30564320 | 0.73 | HSD17B10 (0.69) | HSD17B10ALDH1A1TDP1SMN1; SMN2GAA | |
| SCHEMBL2360248 | 0.73 | HSD17B10 (0.69) | HSD17B10ALDH1A1TDP1SMN1; SMN2GAA | |
| SCHEMBL17727815 | 0.73 | HSD11B1 (0.59) | HSD17B10ALDH1A1TDP1KMT2AMAPT | |
| SCHEMBL31903 | 0.73 | HSD17B10 (0.50) | HSD17B10ALDH1A1TDP1KMT2AMAPT | |
| SCHEMBL27565486 | 0.72 | CA2 (0.72) | CA2CA9CA1ALDH1A1TDP1 | |
| SCHEMBL27273944 | 0.69 | CA2 (0.61) | CA2CA9CA1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |