Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268465 | 0.91 | THRB (0.59) | THRATHRBCYSLTR2CYSLTR1KMT2A | |
| SCHEMBL4666452 | 0.91 | CYSLTR2 (0.54) | THRATHRBCYSLTR2CYSLTR1KMT2A | |
| SCHEMBL204170 | 0.85 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1KMT2AFAAHBRD4 | |
| SCHEMBL4266606 | 0.83 | HPGD (0.50) | THRATHRBKMT2ATDP1L3MBTL1 | |
| SCHEMBL3814672 | 0.83 | L3MBTL1 (0.63) | THRATHRBCYSLTR2CYSLTR1BRD4 | |
| SCHEMBL8955658 | 0.83 | CYSLTR2 (0.63) | THRATHRBCYSLTR2CYSLTR1FAAH | |
| SCHEMBL11112469 | 0.83 | KMT2A (0.50) | THRATHRBCYSLTR2CYSLTR1KMT2A | |
| SCHEMBL10054169 | 0.82 | L3MBTL1 (0.62) | CYSLTR2CYSLTR1KMT2AFAAHBRD4 | |
| SCHEMBL4665843 | 0.81 | ESR1 (0.53) | CYSLTR2CYSLTR1KMT2ABRD4 | |
| SCHEMBL9968921 | 0.81 | TDP1 (0.54) | CYSLTR2CYSLTR1KMT2AFAAHBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | KATAMREDDY SUBBA REDDY | 2008-10-16 | — | — | US | disclosed |
| EP-1951216-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062145-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | GPER1, ESR2, ESRRG | THRA 62/4885THRB 54/4885CYSLTR2 587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.