Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 5/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL4665989 | 0.94 | PRKCA (0.36) | HTR6PRKCAEGFRABCB1ABCG2 | |
| Formic Acid SCHEMBL4666175 | 0.93 | PRKCA (0.39) | HTR6PRKCAEGFRABCB1ABCG2 | |
| Formic Acid SCHEMBL4666097 | 0.87 | PRKCB (0.43) | HTR6PRKCAEGFRABCB1ABCG2 | |
| Formic Acid SCHEMBL4667436 | 0.86 | KMT2A (0.40) | HTR6PRKCAEGFRLCKCDK9 | |
| SCHEMBL4667477 | 0.85 | EGFR (0.35) | PRKCAEGFRABCB1ABCG2LCK | |
| Formic Acid SCHEMBL4663920 | 0.83 | HTR6 (0.46) | HTR6EGFRNR1I2 | |
| SCHEMBL4666179 | 0.82 | PRKCA (0.35) | PRKCAEGFRABCB1ABCG2LCK | |
| Formic Acid SCHEMBL4664281 | 0.81 | HTR6 (0.46) | HTR6EGFRNR1I2 | |
| Formic Acid SCHEMBL4667447 | 0.81 | PRKCB (0.42) | HTR6PRKCAEGFRCYP1A2CYP3A4 | |
| SCHEMBL4663903 | 0.81 | ABCB1 (0.52) | EGFRNR1I2ABCB1ABCG2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | HTR6 826/4885PRKCA 349/4885EGFR 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.