SCHEMBL4667693

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL603516	0.87	OPRM1 (0.59)	CCR5CHRM2CHRM4CHRM5CHRM1
	SCHEMBL31192530	0.86	CHRM1 (0.51)	CCR5CHRM2CHRM4CHRM5CHRM1
	SCHEMBL4636659	0.86	OPRM1 (0.53)	CCR5CHRM2CHRM4CHRM5CHRM1
	SCHEMBL28706667	0.86	OPRM1 (0.57)	CCR5CHRM2CHRM4CHRM5CHRM1
	SCHEMBL8710318	0.86	CHRM1 (0.51)	CCR5CHRM2CHRM4CHRM5CHRM1
	SCHEMBL22587914	0.85	HSD11B1 (0.56)	CCR5CHRM2CHRM4CHRM5CHRM1
	SCHEMBL23540833	0.85	KDM4E (0.51)	CCR5KDM4EMAPTTHRBGPR119
	SCHEMBL22605673	0.84	HSD11B1 (0.56)	CCR5CHRM2CHRM4CHRM5CHRM1
	SCHEMBL4635975	0.84	MAPT (0.51)	CCR5CHRM2CHRM4CHRM5CHRM1
	SCHEMBL22587769	0.84	CCR5 (0.56)	CCR5CHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.