Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.64 |
| ▸ | CA9 | Q16790 | 8/20 | 0.64 |
| ▸ | CA1 | P00915 | 7/20 | 0.64 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 2/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dinitrophenylene SCHEMBL27565505 | 0.93 | CA2 (0.66) | CA2CA9CA1PLAUCA12 | |
| SCHEMBL27565484 | 0.85 | CA2 (0.78) | CA2CA9CA1CA12CA5A | |
| SCHEMBL4667729 | 0.84 | CA2 (0.89) | CA2CA9CA1CA12CA5A | |
| SCHEMBL29832245 | 0.83 | PDE4A (0.55) | CA2CA9CA1PLAUPELI1 | |
| SCHEMBL9451297 | 0.83 | CA2 (0.64) | CA2CA9CA1CA12CA5A | |
| SCHEMBL3519559 | 0.79 | CA2 (1.00) | CA2CA9CA1CA12CA5A | |
| SCHEMBL27565486 | 0.79 | CA2 (0.72) | CA2CA9CA1CA12STS | |
| SCHEMBL8477184 | 0.78 | PLAU (0.62) | PLAULMNATSHR | |
| SCHEMBL4667304 | 0.77 | CA2 (0.65) | CA2CA9CA1CA12STS | |
| SCHEMBL7838339 | 0.77 | LMNA (0.64) | TDP2PGRLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |