Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.65 |
| ▸ | CA9 | Q16790 | 7/20 | 0.65 |
| ▸ | CA1 | P00915 | 6/20 | 0.65 |
| ▸ | STS | P08842 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667729 | 0.82 | CA2 (0.89) | CA2CA9CA1STSCA12 | |
| SCHEMBL27571950 | 0.82 | CA2 (0.53) | CA2CA9CA1STSCA12 | |
| SCHEMBL4667754 | 0.82 | STS (0.67) | CA2CA9CA1STSCA12 | |
| SCHEMBL4667771 | 0.82 | STS (0.67) | CA2CA9CA1STSCA12 | |
| SCHEMBL4667326 | 0.81 | ALDH1A1 (0.57) | CA2CA9CA1STSCA12 | |
| SCHEMBL3519559 | 0.80 | CA2 (1.00) | CA2CA9CA1STSCA12 | |
| SCHEMBL10452690 | 0.79 | PTGS2 (0.52) | CA2CA9CA1CA12TDP1 | |
| SCHEMBL10711868 | 0.77 | TDP1 (0.59) | TDP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4756441 | 0.77 | ALDH1A1 (0.46) | TDP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8065661 | 0.77 | ALDH1A1 (0.46) | TDP1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |