Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.56 |
| ▸ | CA2 | P00918 | 6/20 | 0.56 |
| ▸ | CA9 | Q16790 | 6/20 | 0.56 |
| ▸ | STS | P08842 | 6/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 4/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3857962 | 0.81 | ACLY (0.43) | STSCYP19A1ESR2PTGS2PTGS1 | |
| SCHEMBL4667798 | 0.80 | CA1 (0.54) | CA1CA2CA9STSCYP19A1 | |
| SCHEMBL4667779 | 0.80 | CA2 (0.56) | CA1CA2CA9STSCYP19A1 | |
| SCHEMBL4667168 | 0.80 | CA2 (0.56) | CA1CA2CA9STSCYP19A1 | |
| SCHEMBL22380104 | 0.78 | PTPN1 (0.43) | STSCYP19A1ESR2PTGS2PTGS1 | |
| SCHEMBL4665412 | 0.77 | CYP19A1 (0.56) | CA2STSCYP19A1ESR2PTGS2 | |
| SCHEMBL3375397 | 0.76 | CA2 (0.50) | CA1CA2CA9STSPTGS2 | |
| SCHEMBL10221069 | 0.74 | CA1 (0.76) | CA1CA2CA9STSCYP19A1 | |
| SCHEMBL10172542 | 0.73 | CA1 (0.50) | CA1CA2CA9STSCYP19A1 | |
| SCHEMBL29375895 | 0.73 | ADORA2A (0.55) | ESR2PTGS2PTGS1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |