SCHEMBL4667802

SCHEMBL4667802

CC(O)n1ccc2c(O)cccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 3/20 0.45
HTR6 P50406 1/20 0.41
SLC6A2 P23975 4/20 0.34
SLC6A4 P31645 4/20 0.34
MAPT P10636 2/20 0.33
CYP1A2 P05177 1/20 0.33
HTT P42858 1/20 0.33
APP P05067 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
CASP1 P29466 1/20 0.33
SNCA P37840 1/20 0.33
RECQL P46063 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTR2A P28223 2/20 0.33
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4330148 0.87 HTR2C (0.46) HTR2CHTR6MAPTCYP1A2HTT
SCHEMBL31188171 0.87 HTR2C (0.46) HTR2CHTR6MAPTCYP1A2HTT
SCHEMBL14665265 0.81 HTR2C (0.45) HTR2CHTR6SLC6A2SLC6A4TSHR
SCHEMBL2053714 0.77 HTR2C (0.39) HTR2CHTR6MAPTCYP1A2APP
SCHEMBL28761000 0.76 CA12 (0.39) HTR2CHTR6THRBCA12CA1
SCHEMBL19184503 0.75 HTR2C (0.43) HTR2CHTR6HTR2A
SCHEMBL3251727 0.74 HTR2C (0.56) HTR2CHTR6MAPTTHRBALOX15
SCHEMBL29450529 0.72 HTR2C (0.54) HTR2CHTR6MAPTCYP1A2HTT
SCHEMBL33752 0.72 HTR2C (0.54) HTR2CHTR6MAPTCYP1A2HTT
SCHEMBL4954033 0.71 HTR2C (0.43) HTR2CHTR6MAPTCYP1A2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1342466-B1 Non-colouring composition containing a precursor and a catalyst for oxidative reaction OREAL (FR) 2007-10-17 EP claimed
US-20040016062-A1 Nondyeing composition containing a precursor and an oxidation reaction catalyst L'OREAL (FR) 2004-01-29 US claimed
EP-1329216-B2 Composition for oxidative dyeing of keratinous fibers containing an oxyalkylene ether carboxylic acid, a non-ionic surfactant and a particulate polymer ORÉAL L (FR) 2016-07-06 EP disclosed
EP-1329216-B1 Composition for oxidative dyeing of keratinous fibers containing an oxyalkylene ether carboxylic acid, a non-ionic surfactant and a particulate polymer OREAL (FR) 2008-07-16 EP disclosed
US-7364594-B2 Dyeing composition for keratinous fibres comprising an associative polymer and a polymer with acrylamide units, dialkyldiallylammonium halide, and vinylic carboxylic acid L'OREAL S.A. (FR) 2008-04-29 US disclosed
US-7297167-B2 Composition useful for the oxidation dyeing of keratin fibres, containing a polyoxyalkylenated carboxylic acid ether, a mono- or polyglycerolated surfactant and an unsaturated fatty alcohol L'OREAL (FR) 2007-11-20 US disclosed
US-7223294-B2 Composition for the oxidation dyeing of keratin fibres, comprising a polyoxyalkylenated carboxylic acid ether, an associative polymer and an unsaturated fatty alcohol L'OREAL (FR) 2007-05-29 US disclosed
US-7204858-B2 Composition for the oxidation dyeing of keratin fibres, comprising an oxyalkylenated carboxylic acid ether and a fatty-chain quaternized cellulose L'OREAL (FR) 2007-04-17 US disclosed
US-7153331-B2 Dyeing composition for keratinous fibers comprising an oxyethylene rapeseed fatty acid amide L'OREAL S.A. (FR) 2006-12-26 US disclosed
US-7115147-B2 Composition for the oxidation dyeing of keratin fibres, comprising an oxyalkylenated carboxylic acid ether, a mono- or polyglycerolated surfactant and a nonionic oxyalkylenated surfactant L'OREAL (FR) 2006-10-03 US disclosed
EP-1458338-B1 DYEING COMPOSITION FOR KERATINOUS FIBERS COMPRISING AN OXYETHYLENE RAPESEED FATTY ACID AMIDE OREAL (FR) 2006-09-20 EP disclosed
US-20030182734-A1 Composition for the oxidation dyeing of keratin fibres, comprising an oxyalkylenated carboxylic acid ether and a fatty-chain quaternized cellulose L'OREAL (FR) 2003-10-02 US disclosed
US-20030172473-A1 Composition useful for the oxidation dyeing of keratin fibres, containing an oxyalkylenated carboxylic acid ether, a nonionic surfactant and a particular polymer L'OREAL (FR) 2003-09-18 US disclosed
US-20030172475-A1 Composition useful for the oxidation dyeing of keratin fibres, containing a polyoxyalkylenated carboxylic acid ether, a mono-or polyglycerolated surfactant and an unsaturated fatty alcohol L'OREAL (FR) 2003-09-18 US disclosed
EP-1329216-A1 Composition for oxidative dyeing of keratinous fibers containing an oxyalkylene ether carboxylic acid, a non-ionic surfactant and a particulate polymer L'OREAL (FR) 2003-07-23 EP disclosed
WO-2003053329-A2 DYEING COMPOSITION FOR KERATINOUS FIBERS COMPRISING AN OXYETHYLENE RAPESEED FATTY ACID AMIDE L'OREAL (FR) 2003-07-03 WO disclosed
EP-1323409-A2 Composition for the oxidative dyeing of keratinic fibres containing an oxyalkylenated carboxylic acid-ether and a quaternised cellulose with a fatty chain L'OREAL (FR) 2003-07-02 EP disclosed
EP-1321134-A2 Composition for the oxidative dyeing of keratin fibres containing an oxyalkylenated carboxylic acid ether, an associative polymer and an unsaturated fatty acid L'OREAL (FR) 2003-06-25 EP disclosed
EP-1321135-A2 Composition for the oxidative dyeing of keratin fibres L'OREAL (FR) 2003-06-25 EP disclosed
EP-1321133-A2 Composition for the oxidative dyeing of keratin fibres L'OREAL (FR) 2003-06-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030172473-A1 Composition useful for the oxidation dyeing of keratin fibres, containing an oxyalkylenated carboxylic acid ether, a nonionic surfactant and a particular polymer KRT18, KRTCAP2, CUTA HTR2C 4096/4885HTR6 3295/4885SLC6A2 3703/4885
US-20030182734-A1 Composition for the oxidation dyeing of keratin fibres, comprising an oxyalkylenated carboxylic acid ether and a fatty-chain quaternized cellulose KRT18, FASN, ELOVL5 HTR2C 2920/4885HTR6 1777/4885SLC6A2 3571/4885
US-20040016062-A1 Nondyeing composition containing a precursor and an oxidation reaction catalyst KRT18, CUTA, PPOX HTR2C 3776/4885HTR6 3602/4885SLC6A2 4868/4885
US-20030172475-A1 Composition useful for the oxidation dyeing of keratin fibres, containing a polyoxyalkylenated carboxylic acid ether, a mono-or polyglycerolated surfactant and an unsaturated fatty alcohol KRT18, HACD3, ELOVL5 HTR2C 3100/4885HTR6 3232/4885SLC6A2 4346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.