Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667859 | 0.84 | TRPM8 (0.47) | TRPM8ALDH1A1HPGDPGRADRA2A | |
| SCHEMBL7371261 | 0.81 | TRPM8 (0.45) | TRPM8ALDH1A1HPGDPGRADRA2A | |
| SCHEMBL28182286 | 0.79 | TRPM8 (0.59) | TRPM8ALDH1A1LMNATDP1L3MBTL1 | |
| SCHEMBL10904843 | 0.79 | TRPM8 (0.59) | TRPM8ALDH1A1LMNATDP1L3MBTL1 | |
| SCHEMBL28266347 | 0.78 | TRPM8 (0.43) | TRPM8ALDH1A1HPGDPGRADRA2A | |
| SCHEMBL9508600 | 0.78 | TRPM8 (0.47) | TRPM8ALDH1A1HPGDPGRADRA2A | |
| SCHEMBL28658327 | 0.78 | MLYCD (0.46) | TRPM8ALDH1A1HPGDPGRADRA2A | |
| SCHEMBL18988683 | 0.77 | MLYCD (0.48) | TRPM8ALDH1A1HPGDPGRADRA2A | |
| SCHEMBL31388076 | 0.76 | ADRA2C (0.43) | TRPM8ALDH1A1HPGDHSD11B1MLYCD | |
| SCHEMBL6850539 | 0.76 | TSHR (0.44) | TRPM8ALDH1A1HPGDHSD11B1MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107400057-B | The N- alkylated reaction of nickel catalysis prepares secondary amine or N '-alkyl hydrazine | 山东师范大学 | 2019-09-24 | — | — | CN | disclosed |