Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667859 | 0.81 | TRPM8 (0.47) | TRPM8LMNAALDH1A1POLBMLYCD | |
| SCHEMBL7371261 | 0.78 | TRPM8 (0.45) | TRPM8LMNAALDH1A1POLBMLYCD | |
| SCHEMBL28320439 | 0.78 | TRPM8 (0.45) | TRPM8LMNAALDH1A1POLBMLYCD | |
| SCHEMBL10904843 | 0.76 | TRPM8 (0.59) | TRPM8LMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL28182286 | 0.76 | TRPM8 (0.59) | TRPM8LMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9508600 | 0.75 | TRPM8 (0.47) | TRPM8LMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL18988683 | 0.74 | MLYCD (0.48) | TRPM8LMNAALDH1A1POLBMLYCD | |
| SCHEMBL31388076 | 0.73 | ADRA2C (0.43) | TRPM8ALDH1A1POLBMLYCDSMN1; SMN2 | |
| SCHEMBL5593168 | 0.73 | AOC3 (0.47) | TRPM8ALDH1A1MLYCDHPGDRAB9A | |
| SCHEMBL6850539 | 0.73 | TSHR (0.44) | TRPM8LMNAALDH1A1POLBMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109180621-B | Preparation of Schiff base compounds and application of Schiff base compounds in cancer treatment | 河南省锐达医药科技有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-109180621-A | The preparation and the application in terms for the treatment of of cancer of a kind of New Schiff Base class compound | 河南省锐达医药科技有限公司 | 2019-01-11 | — | — | CN | disclosed |