Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127502 | 0.91 | PRCP (0.37) | PRCPDPP7TLR2NOS2NOS3 | |
| SCHEMBL11376986 | 0.91 | PRCP (0.37) | PRCPDPP7TLR2NOS2NOS3 | |
| SCHEMBL11372054 | 0.86 | PRCP (0.34) | PRCPDPP7TLR2 | |
| SCHEMBL11433291 | 0.84 | CPN1 (0.38) | PRCPDPP7TLR2NOS2NOS3 | |
| SCHEMBL9592134 | 0.81 | NOS2 (0.37) | PRCPDPP7TLR2NOS2NOS3 | |
| SCHEMBL11433189 | 0.81 | PRCP (0.33) | PRCPDPP7TLR2NOS2NOS3 | |
| SCHEMBL1537462 | 0.81 | DPP4 (0.39) | PRCPDPP7NOS2NOS3NOS1 | |
| SCHEMBL1537324 | 0.81 | DPP4 (0.39) | PRCPDPP7NOS2NOS3NOS1 | |
| SCHEMBL11558591 | 0.80 | SLC6A2 (0.39) | PRCPDPP7TLR2NOS2NOS3 | |
| SCHEMBL11434881 | 0.80 | CPN1 (0.35) | PRCPDPP7TLR2NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930021-A2 | Novel amide derivatives as growth hormone secretagogues | Kaken Pharmaceutical Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
| US-7022677-B1 | Amide derivatives as growth hormone secretagogues | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2006-04-04 | — | — | US | disclosed |
| US-20060014701-A1 | Novel amide derivatives as growth hormone secretagogues | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014701-A1 | Novel amide derivatives as growth hormone secretagogues | GHSR, GHRHR, SSTR1 | PRCP 1810/4885DPP7 1419/4885TLR2 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.