SCHEMBL46680

SCHEMBL46680

O=C(O)c1cccc(CCl)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.66
MRGPRX4 Q96LA9 4/20 0.54
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
HIF1A Q16665 1/20 0.53
ANPEP P15144 1/20 0.53
ENPEP Q07075 1/20 0.53
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
NPC1 O15118 1/20 0.53
MITF O75030 1/20 0.53
TP53 P04637 1/20 0.53
HPGD P15428 1/20 0.53
XBP1 P17861 1/20 0.53
NFKB1 P19838 1/20 0.53
RAB9A P51151 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CA12 O43570 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1596805 0.98 FOLH1 (0.63) FOLH1MRGPRX4CYP2D6CYP2C9HIF1A
SCHEMBL28059303 0.85 PLA2G4B (0.51) FOLH1MRGPRX4KMT2ATP53NFKB1
SCHEMBL10622069 0.84 L3MBTL1 (0.63) FOLH1HIF1AHPGDSMN1; SMN2
SCHEMBL27649226 0.84 FOLH1 (0.61) FOLH1MRGPRX4CYP2D6CYP2C9HIF1A
SCHEMBL8581943 0.84 KMO (0.51) FOLH1MRGPRX4KMT2AMEN1NPC1
SCHEMBL28410476 0.83 FOLH1 (0.46) FOLH1MRGPRX4KMT2AMEN1SMN1; SMN2
SCHEMBL39676 0.83 TSHR (0.47) FOLH1MRGPRX4CA1CA2
SCHEMBL29472003 0.83 TSHR (0.47) FOLH1MRGPRX4CA1CA2
SCHEMBL70351 0.83 FOLH1 (0.70) FOLH1CYP2D6CYP2C9HIF1AANPEP
SCHEMBL371526 0.83 FOLH1 (0.70) FOLH1MRGPRX4CYP2D6CYP2C9HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 543 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119034686-A Impurity removing material and preparation method and application thereof 江苏鲁控环境科技有限公司 2024-11-29 CN claimed
CN-118105488-A Diagnosis and treatment prodrug for inducing tumor stem cell apoptosis as well as preparation method and application thereof 东南大学 2024-05-31 CN claimed
CN-116716029-B Long-acting antibacterial and antiviral polyester finishing paint and preparation method thereof 中海油常州涂料化工研究院有限公司 2024-04-30 CN claimed
CN-117603001-A Method for selectively recovering toluene and amyl anthraquinone from alkaline cleaning wastewater 宜昌苏鹏科技有限公司 2024-02-27 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-116716029-A Long-acting antibacterial and antiviral polyester finishing paint and preparation method thereof 中海油常州涂料化工研究院有限公司 2023-09-08 CN claimed
CN-112646159-B Preparation method of quaternary ammonium salt modified polyester resin for antibacterial powder coating 浙江光华科技股份有限公司 2022-09-27 CN claimed
CN-112646159-A Preparation method of quaternary ammonium salt modified polyester resin for antibacterial powder coating 浙江光华科技股份有限公司 2021-04-13 CN claimed
CN-110981719-A Preparation method of 3-carboxyl benzaldehyde 黄石市利福达医药化工有限公司 2020-04-10 CN claimed
CN-109970582-A A method of preparing the chloro- 3- methyl benzoic acid of 2- amino -5- 苏州山青竹生物医药有限公司 2019-07-05 CN claimed
US-20070232514-A1 STABILIZED LIQUID ENZYME COMPOSITION NOVOZYMES A/S (DK) 2007-10-04 US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
EP-1404652-A4 A NOVEL ALKALOID DERIVATIVE AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME CHEMTECH RES INC (KR) 2005-06-15 EP claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
EP-1404652-A1 A NOVEL ALKALOID DERIVATIVE AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME Chemtech Research Incorporation (KR) 2004-04-07 EP claimed
WO-2002100824-A1 A NOVEL ALKALOID DERIVATIVE AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME CHEMTECH RESEARCH INCORPORATION (KR) 2002-12-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 FOLH1 3917/4885MRGPRX4 544/4885CYP2D6 1222/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 FOLH1 4875/4885MRGPRX4 3647/4885CYP2D6 1122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.