SCHEMBL29472003

SCHEMBL29472003

O=C(Cl)c1cccc(CCl)c1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
ALDH1A1 P00352 1/20 0.47
FOLH1 Q04609 1/20 0.46
MRGPRX4 Q96LA9 2/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39676 1.00 TSHR (0.47) TSHRALDH1A1FOLH1MRGPRX4CA1
SCHEMBL7729812 0.88 MRGPRX4 (0.46) TSHRALDH1A1FOLH1MRGPRX4
SCHEMBL4950108 0.85 ALDH1A1 (0.48) TSHRALDH1A1FOLH1MRGPRX4CA1
SCHEMBL5207992 0.84 CYP4F2 (0.45) TSHRALDH1A1FOLH1MRGPRX4LOXL2
SCHEMBL46680 0.83 FOLH1 (0.66) FOLH1MRGPRX4CA1CA2
SCHEMBL16240333 0.83 PRSS1 (0.55) TSHRALDH1A1FOLH1LOXL2CYP4F2
SCHEMBL28410476 0.83 FOLH1 (0.46) TSHRFOLH1MRGPRX4CA1CA2
SCHEMBL46611 0.82 ALDH1A1 (0.46) TSHRALDH1A1FOLH1MRGPRX4LOXL2
SCHEMBL185773 0.82 PARP1 (0.57) TSHRFOLH1MRGPRX4
SCHEMBL18412078 0.82 ALDH1A1 (0.46) TSHRALDH1A1FOLH1MRGPRX4LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119993602-A Carbon nano composite conductive material and application thereof in cable shielding layer 碳境科技(广东)有限公司 2025-05-13 CN claimed
CN-114957156-A Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof 成都科宜高分子科技有限公司 2022-08-30 CN claimed
CN-119993602-A Carbon nano composite conductive material and application thereof in cable shielding layer 碳境科技(广东)有限公司 2025-05-13 CN disclosed
CN-118843616-A Benzamide compounds for the treatment of bacterial infections 豪夫迈·罗氏有限公司 2024-10-25 CN disclosed
CN-114502541-B Compounds inducing expression of anti-aging gene KLOTHO and application thereof 克洛索科学公司 2024-06-07 CN disclosed
CN-115974807-B 2-Phenyl-5-biphenyl-1, 3, 4-oxadiazole compound, preparation method, pharmaceutical composition and application thereof 中国药科大学 2024-05-31 CN disclosed
CN-114644583-B Indole derivative and preparation method and application thereof 中国医学科学院医药生物技术研究所 2024-02-06 CN disclosed
CN-114805341-B Aromatic heterocyclic compound, and preparation method and application thereof 上海翊石医药科技有限公司 2023-12-08 CN disclosed
CN-117157280-A Composition for preventing or treating chronic kidney disease comprising compound inducing expression of anti-aging gene klotho 克洛索科学公司 2023-12-01 CN disclosed
CN-117136055-A Composition for preventing or treating degenerative neurological diseases comprising compound inducing expression of anti-aging gene klotho 克洛索科学公司 2023-11-28 CN disclosed
CN-115974807-A 2-phenyl-5-biphenyl-1,3,4-oxadiazole compound and preparation method, pharmaceutical composition and application thereof 中国药科大学 2023-04-18 CN disclosed
CN-115043860-A Meso-chloromethyl halogenated boron dipyrromethene photosensitizer and application thereof 大连理工大学 2022-09-13 CN disclosed
CN-111032660-B Real-time fluorescence imaging sensor for measuring glutathione in organelles and preparation method thereof 塞尔吐温株式会社 2022-09-02 CN disclosed
CN-114957156-A Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof 成都科宜高分子科技有限公司 2022-08-30 CN disclosed
CN-114805341-A Aromatic heterocyclic compounds and preparation method and application thereof 上海翊石医药科技有限公司 2022-07-29 CN disclosed
CN-114650868-A Small molecule degradation agent of HELIOS and use method thereof 达纳-法伯癌症研究公司 2022-06-21 CN disclosed
CN-114644583-A Indole derivative and preparation method and application thereof 中国医学科学院医药生物技术研究所 2022-06-21 CN disclosed
CN-114173772-A Inhibitors of CD40-CD154 binding 托尼克斯医药控股公司 2022-03-11 CN disclosed
EP-3952853-A1 INHIBITORS OF CD40-CD154 BINDING Tonix Pharmaceuticals Holding Corp. (US) 2022-02-16 EP disclosed