Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.65 |
| ▸ | BACE1 | P56817 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD5 | P21918 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008928 | 0.89 | KDM4E (0.74) | KDM4EMAPTGAAALDH1A1ALOX5 | |
| SCHEMBL272366 | 0.84 | KDM4E (0.68) | KDM4EMAPTGAAALDH1A1ALOX5 | |
| SCHEMBL11970178 | 0.84 | KDM4E (0.57) | KDM4EMAPTGAAALDH1A1ALOX5 | |
| SCHEMBL10409135 | 0.83 | TAAR1 (0.69) | KDM4EMAPTGAAALDH1A1BACE1 | |
| SCHEMBL18928227 | 0.83 | ALDH1A1 (0.65) | KDM4EMAPTGAAALDH1A1ALOX5 | |
| SCHEMBL2342680 | 0.82 | KDM4E (0.71) | KDM4EMAPTGAAALDH1A1ALOX5 | |
| SCHEMBL4720461 | 0.82 | ALDH1A1 (0.52) | KDM4EMAPTGAAALDH1A1ALOX5 | |
| SCHEMBL2786932 | 0.81 | KDM4E (0.63) | KDM4EMAPTGAAALDH1A1ALOX5 | |
| SCHEMBL28177094 | 0.80 | KDM4E (0.68) | KDM4EMAPTGAAALDH1A1ALOX5 | |
| SCHEMBL436819 | 0.79 | MAPT (1.00) | KDM4EMAPTGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8444709-B2 | Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a 2-aminophenol and derivatives thereof | THE PROCTER & GAMBLE COMPANY (US) | 2013-05-21 | — | — | US | claimed |
| WO-2013058816-A1 | OXIDATIVE DYEING COMPOSITIONS COMPRISING AN 1-HEXYL/HEPTYL-4,5-DIAMINOPYRAZOLE AND A 2-AMINOPHENOL AND DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2013-04-25 | — | — | WO | claimed |
| US-20120210519-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a 2-Aminophenol and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | claimed |
| CN-107072920-B | Hair colouring layer, method and kit therefor | 诺赛尔股份有限公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-107072923-B | Hair colouring layer, method and kit therefor | 诺赛尔股份有限公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-107072899-B | Hair treatment composition, kit and method thereof | 诺赛尔股份有限公司 | 2020-12-25 | — | — | CN | disclosed |
| EP-1992331-B1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | OREAL (FR) | 2013-10-02 | — | — | EP | disclosed |
| US-8444709-B2 | Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a 2-aminophenol and derivatives thereof | THE PROCTER & GAMBLE COMPANY (US) | 2013-05-21 | — | — | US | disclosed |
| WO-2013058816-A1 | OXIDATIVE DYEING COMPOSITIONS COMPRISING AN 1-HEXYL/HEPTYL-4,5-DIAMINOPYRAZOLE AND A 2-AMINOPHENOL AND DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2013-04-25 | — | — | WO | disclosed |
| US-20120210519-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a 2-Aminophenol and Derivatives Thereof | WELLA OPERATIONS US, LLC | 2012-08-23 | — | — | US | disclosed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120210519-A1 | Oxidative Dyeing Compositions Comprising an 1-Hexyl/Heptyl-4,5-diaminopyrazole and a 2-Aminophenol and Derivatives Thereof | TYR, GPX4, TH | KDM4E 1009/4885MAPT 3760/4885GAA 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.