Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258555 | 0.76 | PDE2A (0.39) | PDE2AALDH1A1HTTSMN1; SMN2MRGPRX4 | |
| SCHEMBL5743667 | 0.73 | ALDH1A1 (0.34) | PDE2AALDH1A1HTTSMN1; SMN2MRGPRX4 | |
| SCHEMBL6576617 | 0.67 | — | — | |
| SCHEMBL9704905 | 0.66 | MAPT (0.39) | PDE2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5744940 | 0.65 | MRGPRX4 (0.37) | PDE2AALDH1A1HTTSMN1; SMN2MRGPRX4 | |
| SCHEMBL9704423 | 0.64 | MRGPRX4 (0.33) | MRGPRX4 | |
| SCHEMBL10437726 | 0.64 | MAPT (0.37) | PDE2AALDH1A1HTT | |
| SCHEMBL9703422 | 0.63 | MRGPRX4 (0.34) | ALDH1A1HTTSMN1; SMN2MRGPRX4 | |
| SCHEMBL9768338 | 0.63 | PDE2A (0.38) | PDE2AALDH1A1MRGPRX4 | |
| SCHEMBL9704767 | 0.61 | PDE2A (0.37) | PDE2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323574-B2 | Process for the preparation of phenyl pyrazole compounds | BASF AGRO B.V. ARNHEM (CH) | 2008-01-29 | — | — | US | disclosed |
| US-20070021620-A1 | Process for the preparation of phenyl pyrazole compounds | MERIAL LIMITED | 2007-01-25 | — | — | US | disclosed |
| US-7129372-B2 | Process for the preparation of phenyl pyrazole compounds | BASF Agro B.V., Amhem (NL)—Wadenswil Branch (CH) | 2006-10-31 | — | — | US | disclosed |
| EP-1378506-B1 | Process for the preparation of phenyl pyrazole compounds | BASF AGRO B V ARNHEM NL WAEDEN (CH) | 2006-07-26 | — | — | EP | disclosed |
| US-20060052614-A1 | Process for the preparation of phenyl pyrazole compounds | MERIAL LIMITED | 2006-03-09 | — | — | US | disclosed |
| EP-1378506-A1 | Process for the preparation of phenyl pyrazole compounds | Bayer CropScience S.A. (FR) | 2004-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021620-A1 | Process for the preparation of phenyl pyrazole compounds | ALG3, KCNH3, KCNA3 | PDE2A 4158/4885ALDH1A1 1848/4885HTT 3220/4885 |
| US-20060052614-A1 | Process for the preparation of phenyl pyrazole compounds | F5, CYP4F3, ALG3 | PDE2A 4078/4885ALDH1A1 1595/4885HTT 3549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.