Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704767 | 0.84 | PDE2A (0.37) | PDE2AMAPTALDH1A1PDK2KDM4E | |
| SCHEMBL9704905 | 0.77 | MAPT (0.39) | PDE2AMAPTALDH1A1GAA | |
| SCHEMBL5744940 | 0.74 | MRGPRX4 (0.37) | PDE2AALDH1A1PDK2MRGPRX4 | |
| SCHEMBL6258555 | 0.69 | PDE2A (0.39) | PDE2AMAPTALDH1A1PDK2NR1H3 | |
| SCHEMBL1768930 | 0.68 | PDE2A (0.49) | PDE2AMAPTALDH1A1PDK2KDM4E | |
| SCHEMBL13707569 | 0.67 | PDE2A (0.45) | PDE2AMAPTALDH1A1KDM4ECYP1A2 | |
| SCHEMBL4373756 | 0.67 | PDE2A (0.45) | PDE2AMAPTALDH1A1KDM4ECYP1A2 | |
| SCHEMBL4373753 | 0.67 | PDE2A (0.45) | PDE2AMAPTALDH1A1KDM4ECYP1A2 | |
| SCHEMBL5743667 | 0.67 | ALDH1A1 (0.34) | PDE2AMAPTALDH1A1PDK2KDM4E | |
| SCHEMBL10437726 | 0.67 | MAPT (0.37) | PDE2AMAPTALDH1A1PDK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064844-A | Miticides | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-11-12 | — | — | US | disclosed |
| EP-0350237-A2 | Triazole insecticides | SCHERING AGROCHEMICALS LIMITED (GB) | 1990-01-10 | — | — | EP | disclosed |