Glutamic Acid

Glutamic Acid

SCHEMBL4669203

CC(C)(C)OC(=O)N[C@@H](CCC(=O)O)C(=O)OCc1ccccc1.N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.52
PPARG P37231 4/20 0.49
ACE P12821 1/20 0.48
LTA4H P09960 1/20 0.47
CTSS P25774 4/20 0.47
FOLH1 Q04609 3/20 0.47
SYK P43405 1/20 0.47
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
CTSK P43235 2/20 0.46
PPARD Q03181 2/20 0.45
CTSL P07711 1/20 0.45
CTSB P07858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203720 0.92 PPARA (0.56) PPARAPPARGACECTSSFOLH1
SCHEMBL2707177 0.92 PPARA (0.56) PPARAPPARGACECTSSFOLH1
SCHEMBL957159 0.92 PPARA (0.56) PPARAPPARGACECTSSFOLH1
SCHEMBL2899548 0.85 PPARA (0.54) PPARAPPARGACECTSSSYK
SCHEMBL10883348 0.85 PPARA (0.54) PPARAPPARGACECTSSSYK
SCHEMBL10054776 0.85 PPARA (0.56) PPARAPPARGACECTSSSYK
SCHEMBL27578688 0.85 PPARA (0.56) PPARAPPARGACECTSSSYK
SCHEMBL1517760 0.84 PPARA (0.55) PPARAPPARGACECTSSSYK
SCHEMBL14674671 0.84 CTSS (0.54) PPARAPPARGCTSSSYKITGB3
SCHEMBL3817109 0.84 PPARA (0.55) PPARAPPARGACECTSSSYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080275139-A1 Cyclodextrin-Containing Polymers and Uses Thereof CAPSUTECH LTD. (IL) 2008-11-06 US disclosed
EP-1976546-A2 CYCLODEXTRIN-CONTAINING POLYMERS AND USES THEREOF Capsutech Ltd. (IL) 2008-10-08 EP disclosed
WO-2007072481-A2 CYCLODEXTRIN-CONTAINING POLYMERS AND USES THEREOF CAPSUTECH LTD. (IL) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275139-A1 Cyclodextrin-Containing Polymers and Uses Thereof IAPP, RNGTT, DDOST PPARA 2035/4885PPARG 3165/4885ACE 2317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.