Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SFRP1 | Q8N474 | 3/20 | 0.41 |
| ▸ | WNT3 | P56703 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4201103 | 0.91 | HTR6 (0.48) | HTR6NAMPTALDH1A1SFRP1WNT3 | |
| SCHEMBL15867028 | 0.83 | VCAM1 (0.48) | LMNANAMPTMAPTSLC22A12AR | |
| SCHEMBL10430026 | 0.79 | HTR6 (0.47) | LMNAHTR6TSHRALDH1A1PKM | |
| Sulfuric Acid SCHEMBL8328478 | 0.78 | TSHR (0.52) | TSHRCYP3A4ALDH1A1POLBGLA | |
| SCHEMBL29422813 | 0.78 | GAA (0.64) | TSHRALDH1A1POLBGLAGAA | |
| SCHEMBL146397 | 0.78 | GAA (0.64) | TSHRALDH1A1POLBGLAGAA | |
| SCHEMBL19604031 | 0.77 | KIF11 (0.50) | LMNANAMPTMAPTSLC22A12PGAM1 | |
| SCHEMBL4618091 | 0.77 | FFAR4 (0.49) | LMNAHTR6ALDH1A1PKMSFRP1 | |
| Hydrochloric Acid SCHEMBL31582982 | 0.76 | GAA (0.61) | TSHRALDH1A1POLBGLAGAA | |
| Hydrochloric Acid SCHEMBL4372872 | 0.76 | GAA (0.61) | TSHRALDH1A1POLBGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937632-A1 | NOVEL COMPOUNDS | Astra Zeneca AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007039736-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-04-12 | — | — | WO | disclosed |