Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4149967 | 0.89 | MAPT (0.39) | TLR7MEN1USP2MAPTALOX15 | |
| SCHEMBL4636118 | 0.74 | CES2 (0.33) | DHODHKAT6AMEN1USP2MAPT | |
| SCHEMBL4636352 | 0.74 | P2RX7 (0.33) | DHODH | |
| SCHEMBL4150885 | 0.72 | MEN1 (0.39) | TLR7MEN1USP2MAPTALOX15 | |
| SCHEMBL4158322 | 0.72 | ATM (0.37) | TLR7MEN1USP2MAPTALOX15 | |
| SCHEMBL4637507 | 0.70 | RXFP1 (0.35) | KAT6AMAPTCES2BCHECES1 | |
| SCHEMBL4155015 | 0.70 | TLR7 (0.40) | TLR7MAPTRORC | |
| SCHEMBL13774580 | 0.69 | MAPT (0.50) | TLR7MEN1USP2MAPTALOX15 | |
| SCHEMBL4637632 | 0.69 | CES2 (0.33) | KAT6AMAPTCES2BCHECES1 | |
| SCHEMBL4636520 | 0.69 | KAT6A (0.38) | KAT6ACES2BCHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |