SCHEMBL466974

SCHEMBL466974

COc1cccc2c1CCCC2CCCN1CCN(C2CCCCC2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 11/20 1.00
CHRM2 P08172 1/20 1.00
CHRM4 P08173 1/20 1.00
ABCB1 P08183 1/20 1.00
CHRM5 P08912 1/20 1.00
ADRA2A P08913 1/20 1.00
CHRM1 P11229 1/20 1.00
ADRA2B P18089 1/20 1.00
ADRA2C P18825 1/20 1.00
CHRM3 P20309 1/20 1.00
KCNH2 Q12809 1/20 1.00
TMEM97 Q5BJF2 1/20 1.00
HTR1A P08908 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31060454 1.00 SIGMAR1 (1.00) SIGMAR1CHRM2CHRM4ABCB1CHRM5
Hydrochloric Acid SCHEMBL20271899 0.99 SIGMAR1 (0.98) SIGMAR1CHRM2CHRM4ABCB1CHRM5
Hydrochloric Acid SCHEMBL29463387 0.99 SIGMAR1 (0.98) SIGMAR1CHRM2CHRM4ABCB1CHRM5
SCHEMBL12673206 0.96 SIGMAR1 (1.00) SIGMAR1CHRM2CHRM4ABCB1CHRM5
SCHEMBL25066829 0.92 SIGMAR1 (0.85) SIGMAR1CHRM2CHRM4ABCB1CHRM5
SCHEMBL31061066 0.84 SIGMAR1 (0.73) SIGMAR1CHRM2CHRM4ABCB1CHRM5
SCHEMBL8000332 0.84 SIGMAR1 (0.72) SIGMAR1CHRM2CHRM4ABCB1CHRM5
SCHEMBL9247478 0.83 SIGMAR1 (1.00) SIGMAR1HTR1A
SCHEMBL9249152 0.83 SIGMAR1 (1.00) SIGMAR1HTR1A
SCHEMBL8021562 0.82 SIGMAR1 (0.70) SIGMAR1CHRM2CHRM4ABCB1CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125762-A1 METHODS OF IDENTIFYING AND TREATING TUMORS WITH SIGMA1 INHIBITORS UNIV DREXEL (US) 2026-05-07 US claimed
US-20250304793-A1 COLORED TITANIUM DIOXIDE ASPHALT COMPOSITIONS COOLSEAL LLC 2025-10-02 US claimed
US-20250084279-A1 TRANSPARENT MATTE ANTI-STAIN CORROSION-RESISTANT SURFACE COATING AND COLORED ANTI-STAIN CORROSION-RESISTANT SURFACE COATING FOR DIRECT AMBIENT TEMPERATURE MOISTURE-CURED TOPCOAT APPLICATIONS RAYOUNG CHEMTECH INC. (TW) 2025-03-13 US claimed
CN-118995046-A Colored anti-fouling and corrosion-resistant surface coating, application thereof, colored anti-fouling and corrosion-resistant surface layer and colored anti-fouling and corrosion-resistant metal 雷旸科技实业股份有限公司 2024-11-22 CN claimed
CN-115799787-B LTCC band-pass filter with high suppression degree 扬州江嘉科技有限公司 2024-10-01 CN claimed
EP-4426729-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 EP claimed
US-20240254561-A1 METHODS OF IDENTIFYING AND TREATING TUMORS WITH SIGMA1 INHIBITORS THOMAS JEFFERSON UNIVERSITY 2024-08-01 US claimed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN claimed
EP-4326822-A1 COLORED TITANIUM DIOXIDE ASPHALT COMPOSITIONS CoolSeal LLC (US) 2024-02-28 EP claimed
EP-4314018-A1 METHODS AND COMPOSITIONS FOR HIGH-POTENCY POLYPEPTIDE-BASED PROTEIN INHIBITION Baylor College of Medicine (US) 2024-02-07 EP claimed
EP-4149496-A1 SARS-COV-2-SPECIFIC T CELLS Board of Regents, The University of Texas System (US) 2023-03-22 EP claimed
CN-115799787-A LTCC band-pass filter with high suppression degree 扬州江嘉科技有限公司 2023-03-14 CN claimed
US-20230010108-A1 A CONJUGATION LINKER CONTAINING 2,3-DIAMINOSUCCINYL GROUP HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-01-12 US claimed
US-20220401553-A1 PARAPOXVIRUS FOR CONDITIONING FOR AND TREATMENT OF CORONAVIRUS INFECTIONS AICURIS GMBH & CO. KG (DE) 2022-12-22 US claimed
WO-2022225662-A1 COLORED TITANIUM DIOXIDE ASPHALT COMPOSITIONS GuardTop, LLC (US) 2022-10-27 WO claimed
WO-2022213076-A1 METHODS AND COMPOSITIONS FOR HIGH-POTENCY POLYPEPTIDE-BASED PROTEIN INHIBITION BAYLOR COLLEGE OF MEDICINE (US) 2022-10-06 WO claimed
EP-3906970-B1 PARAPOXVIRUS FOR CONDITIONING AND TREATMENT OF CORONAVIRUS INFECTIONS AICURIS GMBH & CO KG (DE) 2022-07-06 EP claimed
US-20220193204-A1 USES OF A2 DOMAIN OF VON WILLEBRAND FACTOR BAYLOR COLLEGE OF MEDICINE (US) 2022-06-23 US claimed
CN-216514469-U Multi-guide-bar device for lace and warp knitting and warp-knitted spacer fabric cloth thereof 福建省晋江市华宇织造有限公司 2022-05-13 CN claimed
EP-3969036-A1 USES OF A2 DOMAIN OF VON WILLEBRAND FACTOR Baylor College of Medicine (US) 2022-03-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230010108-A1 A CONJUGATION LINKER CONTAINING 2,3-DIAMINOSUCCINYL GROUP DAO, DDO, DCLRE1A SIGMAR1 1688/4885CHRM2 4299/4885CHRM4 4536/4885
US-20240254561-A1 METHODS OF IDENTIFYING AND TREATING TUMORS WITH SIGMA1 INHIBITORS SIGMAR1, TMEM97, OPRK1 SIGMAR1 1/4885CHRM2 3184/4885CHRM4 2292/4885
US-20260125762-A1 METHODS OF IDENTIFYING AND TREATING TUMORS WITH SIGMA1 INHIBITORS IGF2BP3, RBM3, MORF4L1 SIGMAR1 9/4885CHRM2 1493/4885CHRM4 1258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.