Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2404150 | 0.79 | OPRM1 (0.40) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11491487 | 0.76 | GRIN2D (0.37) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6102182 | 0.75 | GABRA1 (0.40) | — | |
| SCHEMBL6102179 | 0.75 | GABRA1 (0.40) | — | |
| SCHEMBL6102173 | 0.75 | GABRA1 (0.40) | — | |
| SCHEMBL6103283 | 0.72 | EGFR (0.35) | — | |
| SCHEMBL5708801 | 0.72 | EGFR (0.35) | — | |
| SCHEMBL28026032 | 0.71 | OPRM1 (0.46) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL410055 | 0.70 | OPRM1 (0.44) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31124279 | 0.70 | OPRM1 (0.44) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008125230-A2 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED AMINOHETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008125230-A2 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED AMINOHETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| EP-1982595-A1 | Insecticidal derivatives of substituted aminoheterocycles | Bayer CropScience AG (DE) | 2008-10-22 | — | — | EP | disclosed |