Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 9/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708801 | 1.00 | EGFR (0.35) | EGFRPYGLFFAR1NAAAMTNR1A | |
| SCHEMBL11287590 | 0.74 | TSHR (0.49) | EGFRPYGLMTNR1AMTNR1BMEN1 | |
| SCHEMBL11287585 | 0.74 | TSHR (0.49) | EGFRPYGLMTNR1AMTNR1BMEN1 | |
| SCHEMBL11291868 | 0.74 | TSHR (0.49) | EGFRPYGLMTNR1AMTNR1BMEN1 | |
| SCHEMBL8582012 | 0.73 | SLC6A12 (0.41) | EGFRPYGL | |
| SCHEMBL4670580 | 0.72 | OPRM1 (0.37) | — | |
| SCHEMBL6102173 | 0.71 | GABRA1 (0.40) | MTNR1AMTNR1BGAA | |
| SCHEMBL6102182 | 0.71 | GABRA1 (0.40) | MTNR1AMTNR1BGAA | |
| SCHEMBL6102179 | 0.71 | GABRA1 (0.40) | MTNR1AMTNR1BGAA | |
| SCHEMBL8296922 | 0.71 | PYGL (0.41) | PYGLMTNR1AMTNR1BMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060040919-A1 | Bronchorelaxing compounds | RESPIRATORIUS AB (SE) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040919-A1 | Bronchorelaxing compounds | CHRM3, GPR3, CHRM2 | EGFR 2334/4885PYGL 3878/4885FFAR1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.