Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666017 | 0.83 | NTRK1 (0.36) | ALDH1A1KDM4ENTRK1HSD17B10HPGD | |
| SCHEMBL6665543 | 0.82 | LMNA (0.30) | — | |
| SCHEMBL6665727 | 0.82 | — | — | |
| SCHEMBL6663022 | 0.82 | IKBKE (0.32) | — | |
| SCHEMBL6666212 | 0.80 | MTNR1A (0.40) | ALDH1A1PFKFB3 | |
| SCHEMBL6664626 | 0.78 | MAP3K12 (0.32) | NTRK1 | |
| SCHEMBL7920973 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KDM4ENTRK1HSD17B10HPGD | |
| SCHEMBL843352 | 0.71 | ALDH1A1 (0.37) | ALDH1A1KDM4ENTRK1HSD17B10HPGD | |
| SCHEMBL24664975 | 0.70 | NOS3 (0.43) | — | |
| SCHEMBL843607 | 0.70 | NTRK1 (0.40) | ALDH1A1KDM4ENTRK1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1116795-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE PYRIDINEETHANOL DERIVATIVES | KANEKA CORP (JP) | 2008-03-12 | — | — | EP | disclosed |
| US-7329518-B2 | Enzyme for producing optically active pyridineethanol derivatives | KANEKA CORPORATION (JP) | 2008-02-12 | — | — | US | disclosed |
| EP-0824524-B1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | UPJOHN CO (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1449835-A2 | Alpha-substituted pyrimidine-thioalkyl and alkylether compounds | PHARMACIA & UPJOHN COMPANY (US) | 2004-08-25 | — | — | EP | disclosed |
| US-20040043460-A1 | Process for producing optically active pyridineethanol derivatives | KANEKA CORPORATION (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1116795-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE PYRIDINEETHANOL DERIVATIVES | KANEKA CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| US-6043248-A | VIRICIDES FOR TREATING AN INDIVIDUAL INFECTED WITH THE HUMAN IMMUNODEFICIENCY VIRUS | PHARMACIA & UPJOHN COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0824524-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035678-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1996-11-14 | — | — | WO | disclosed |