Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | TACR3 | P29371 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638545 | 0.93 | ALDH1A1 (0.38) | ALDH1A1NLRP3EPAS1GPBAR1MEN1 | |
| SCHEMBL4637922 | 0.93 | TACR1 (0.36) | ALDH1A1NLRP3EPAS1GPBAR1MEN1 | |
| SCHEMBL4637945 | 0.88 | EPAS1 (0.37) | ALDH1A1NLRP3EPAS1GPBAR1MEN1 | |
| SCHEMBL4637843 | 0.86 | GPBAR1 (0.38) | ALDH1A1NLRP3EPAS1GPBAR1MEN1 | |
| SCHEMBL4639007 | 0.84 | GPBAR1 (0.37) | ALDH1A1NLRP3EPAS1GPBAR1TSHR | |
| SCHEMBL4637747 | 0.81 | EPAS1 (0.38) | ALDH1A1NLRP3EPAS1GPBAR1MEN1 | |
| SCHEMBL4639351 | 0.81 | USP2 (0.39) | ALDH1A1NLRP3EPAS1GPBAR1MAPT | |
| SCHEMBL4637876 | 0.81 | EPAS1 (0.39) | ALDH1A1NLRP3EPAS1GPBAR1MEN1 | |
| SCHEMBL4637694 | 0.81 | EPAS1 (0.39) | ALDH1A1NLRP3EPAS1GPBAR1MEN1 | |
| SCHEMBL4638045 | 0.80 | EPAS1 (0.39) | ALDH1A1NLRP3EPAS1GPBAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501808-B1 | TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-07-02 | — | — | EP | disclosed |