Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276972 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL4672367 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL2427784 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL29548152 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL28734857 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL27638392 | 0.81 | BRD4 (0.43) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL14147250 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL22863726 | 0.80 | CA1 (0.39) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL10360804 | 0.80 | ALDH1A1 (0.77) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL70322 | 0.80 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRHSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888233-A2 | HETEROGENEOUS ALKYNE METATHESIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006135631-A2 | HETEROGENEOUS ALKYNE METATHESIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2006-12-21 | — | — | WO | disclosed |
| US-20060281938-A1 | HETEROGENEOUS ALKYNE METATHESIS | ENERGY, UNITED STATES DEPARTMENT OF | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281938-A1 | HETEROGENEOUS ALKYNE METATHESIS | SOD1, DNMT1, SCO2 | ALDH1A1 842/4885LMNA 3054/4885TSHR 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.