Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.62 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.60 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.60 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PTPRB | P23467 | 1/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40546 | 0.86 | CYP4F2 (0.63) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL7276383 | 0.84 | LOXL2 (0.66) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL31044528 | 0.84 | LOXL2 (0.57) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL3932722 | 0.84 | LOXL2 (0.57) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL29539688 | 0.83 | LOXL2 (0.64) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL40562 | 0.83 | LOXL2 (0.64) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL21936783 | 0.83 | LOXL2 (0.64) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL576723 | 0.82 | FOLH1 (0.56) | MRGPRX4SMN1; SMN2RAB9AHIF1AFOLH1 | |
| SCHEMBL70173 | 0.80 | CYP4F2 (0.83) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL126284 | 0.80 | LOXL2 (0.74) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888233-A2 | HETEROGENEOUS ALKYNE METATHESIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006135631-A2 | HETEROGENEOUS ALKYNE METATHESIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2006-12-21 | — | — | WO | disclosed |
| US-20060281938-A1 | HETEROGENEOUS ALKYNE METATHESIS | ENERGY, UNITED STATES DEPARTMENT OF | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281938-A1 | HETEROGENEOUS ALKYNE METATHESIS | SOD1, DNMT1, SCO2 | LOXL2 1178/4885CYP4F2 1183/4885CYP4A11 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.