Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 7/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 7/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793425 | 0.87 | CYP26A1 (0.36) | MEN1KMT2AAAK1FPR2MAPT | |
| SCHEMBL4818195 | 0.83 | KCNQ3 (0.41) | ALDH1A1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL4669026 | 0.79 | TNF (0.38) | ALDH1A1MEN1KMT2ALMNAKCNQ3 | |
| Hydrochloric Acid SCHEMBL4823521 | 0.78 | TNF (0.37) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3785603 | 0.76 | FNTA (0.37) | P2RX3 | |
| SCHEMBL3768495 | 0.74 | SSTR5 (0.37) | AAK1 | |
| SCHEMBL3776782 | 0.72 | CHEK1 (0.41) | AAK1 | |
| SCHEMBL3781094 | 0.70 | KMO (0.38) | MEN1KMT2ARAB9A | |
| SCHEMBL29819093 | 0.70 | POLB (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4817839 | 0.70 | GRM5 (0.39) | ALDH1A1RAB9AGAAKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757586-B1 | POLYSBUSTITUIRTE 1,1-PYRIDINYLAMINOCYCLOPROPANAMIN DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE ENTHALTENDE PHARMATUETISCHE ZUSAMMENSETZUNG | SERVIER LAB (FR) | 2008-12-03 | — | — | EP | disclosed |
| EP-1757586-A1 | POLYSBUSTITUIRTE 1,1-PYRIDINYLAMINOCYCLOPROPANAMIN DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE ENTHALTENDE PHARMATUETISCHE ZUSAMMENSETZUNG | Les Laboratoires Servier (FR) | 2007-02-28 | — | — | EP | disclosed |