Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 3/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 14/20 | 0.34 |
| ▸ | BRAF | P15056 | 11/20 | 0.34 |
| ▸ | ADH5 | P11766 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3776782 | 0.84 | CHEK1 (0.41) | SSTR5AAK1 | |
| SCHEMBL3778732 | 0.83 | MAP4K4 (0.34) | SSTR5ADH5 | |
| SCHEMBL3785603 | 0.81 | FNTA (0.37) | RAF1BRAF | |
| SCHEMBL3147370 | 0.78 | ABL1 (0.36) | SSTR5RAF1BRAF | |
| SCHEMBL3151064 | 0.77 | RAF1 (0.38) | RAF1BRAF | |
| SCHEMBL3781094 | 0.76 | KMO (0.38) | — | |
| Hydrochloric Acid SCHEMBL3776849 | 0.76 | SYK (0.39) | SSTR5RAF1BRAF | |
| SCHEMBL4672927 | 0.74 | MAPKAPK2 (0.36) | AAK1 | |
| SCHEMBL4793425 | 0.74 | CYP26A1 (0.36) | AAK1 | |
| SCHEMBL3779611 | 0.74 | RXRA (0.35) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | LES LABORATOIRES SERVIER (FR) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | CHRNA6, CHRNE, CHRNG | SSTR5 415/4885AAK1 4282/4885RAF1 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.