Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.37 |
| ▸ | FNTB | P49356 | 6/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | EIF4EBP1 | Q13541 | 3/20 | 0.34 |
| ▸ | DDT | P30046 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147123 | 0.84 | PTGER1 (0.35) | PTGER1DDTUSP30 | |
| SCHEMBL3781094 | 0.84 | KMO (0.38) | FNTAFNTBPGGT1BUSP30 | |
| SCHEMBL3768495 | 0.81 | SSTR5 (0.37) | RAF1BRAF | |
| Hydrochloric Acid SCHEMBL3774096 | 0.77 | FNTA (0.40) | FNTAFNTBPGGT1BPTGER1EIF4EBP1 | |
| SCHEMBL3776782 | 0.76 | CHEK1 (0.41) | — | |
| SCHEMBL4672927 | 0.76 | MAPKAPK2 (0.36) | P2RX3 | |
| SCHEMBL3776682 | 0.75 | JMJD6 (0.36) | — | |
| SCHEMBL3779611 | 0.75 | RXRA (0.35) | PTGER1DDTRAF1BRAF | |
| SCHEMBL3767931 | 0.74 | RXRA (0.36) | PTGER1DDT | |
| SCHEMBL3146191 | 0.74 | MAP4K4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | LES LABORATOIRES SERVIER (FR) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | CHRNA6, CHRNE, CHRNG | FNTA 3433/4885FNTB 1606/4885PGGT1B 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.