Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267089 | 0.75 | HTR2A (0.43) | JAK3 | |
| SCHEMBL4679150 | 0.73 | CASP3 (0.41) | MAPTCASP1 | |
| SCHEMBL4673620 | 0.73 | CDK1 (0.33) | MAPTCASP1 | |
| SCHEMBL4864975 | 0.72 | MAPT (0.44) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL33961 | 0.72 | MAPT (0.44) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL4677485 | 0.72 | CHUK (0.39) | CASP1 | |
| Hydrochloric Acid SCHEMBL970834 | 0.70 | MAPT (0.42) | MAPTCASP1AURKATTKAURKB | |
| Hydrochloric Acid SCHEMBL2479718 | 0.70 | MAPT (0.42) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL4674001 | 0.70 | MAP4K4 (0.41) | JAK3 | |
| SCHEMBL4679046 | 0.69 | ADORA3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457199-B1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | OREAL (FR) | 2008-05-14 | — | — | EP | disclosed |
| US-7175670-B2 | Couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| US-20050081313-A1 | Novel couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2005-04-21 | — | — | US | disclosed |
| EP-1459732-A1 | Dye composition comprising at least one heterocyclic oxidation base and at least one 2,3,5-triaminopyridine as coupler | L'OREAL (FR) | 2004-09-22 | — | — | EP | disclosed |
| EP-1457199-A1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-15 | — | — | EP | disclosed |