Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251657 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL4673620 | 0.79 | CDK1 (0.33) | MAPTCASP1HRH4 | |
| SCHEMBL4677485 | 0.77 | CHUK (0.39) | MEN1KMT2AKDM4EALDH1A1CASP1 | |
| SCHEMBL4674001 | 0.75 | MAP4K4 (0.41) | HRH4 | |
| SCHEMBL4864975 | 0.74 | MAPT (0.44) | MEN1KMT2AMAPTALDH1A1CASP1 | |
| SCHEMBL33961 | 0.74 | MAPT (0.44) | MEN1KMT2AMAPTALDH1A1CASP1 | |
| SCHEMBL4673036 | 0.73 | MAPT (0.34) | MAPTCASP1 | |
| Hydrochloric Acid SCHEMBL970834 | 0.72 | MAPT (0.42) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2479718 | 0.72 | MAPT (0.42) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2412222 | 0.72 | CNR2 (0.43) | SMN1; SMN2HRH4NUDT1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457199-B1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | OREAL (FR) | 2008-05-14 | — | — | EP | disclosed |
| US-7175670-B2 | Couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| US-20050081313-A1 | Novel couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2005-04-21 | — | — | US | disclosed |
| EP-1459732-A1 | Dye composition comprising at least one heterocyclic oxidation base and at least one 2,3,5-triaminopyridine as coupler | L'OREAL (FR) | 2004-09-22 | — | — | EP | disclosed |
| EP-1457199-A1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-15 | — | — | EP | disclosed |