Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672410 | 0.91 | HPGD (0.54) | HPGDTSHRDPP4KMT2AALDH1A1 | |
| SCHEMBL4671695 | 0.72 | KMT2A (0.45) | HPGDTSHRHTTKMT2AALDH1A1 | |
| SCHEMBL27487700 | 0.70 | KMT2A (0.43) | HPGDTSHRDPP4KMT2AALDH1A1 | |
| SCHEMBL2525981 | 0.68 | ALDH1A1 (0.60) | HPGDTSHRHTTKMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL12493760 | 0.68 | L3MBTL1 (0.78) | HTTKMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL1902358 | 0.68 | SMN1; SMN2 (0.76) | HPGDTSHRHTTKMT2AALDH1A1 | |
| SCHEMBL1665525 | 0.67 | HPGD (0.56) | HPGDTSHRHTTP2RX7DPP4 | |
| SCHEMBL4922178 | 0.67 | HPGD (0.64) | HPGDTSHRHTTDPP4KMT2A | |
| SCHEMBL11021735 | 0.67 | HPGD (0.64) | HPGDTSHRHTTDPP4ALDH1A1 | |
| SCHEMBL31190825 | 0.67 | HPGD (0.64) | HPGDTSHRHTTDPP4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304329-B1 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI SANKYO CO LTD (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5849757-A | Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| CN-1179155-A | Heterocyclic compounds | DAIICHI PHARMACEUTICLA CO LTD (JP) | 1998-04-15 | — | — | CN | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |