Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 10/20 | 0.35 |
| ▸ | CPB1 | P15086 | 4/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026161 | 0.81 | CPB2 (0.40) | ALDH1A1AKR1B1CPB2CPB1CSNK2A2 | |
| SCHEMBL239541 | 0.79 | CYP2C9 (0.49) | ALDH1A1TAAR1AKR1B1CPB2CPB1 | |
| Hydrochloric Acid SCHEMBL9803746 | 0.77 | TDP1 (0.50) | ALDH1A1TAAR1AKR1B1CPB2CPB1 | |
| SCHEMBL11309741 | 0.77 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1TAAR1AKR1B1CSNK2A2 | |
| SCHEMBL1911274 | 0.75 | CPB2 (0.46) | ALDH1A1TAAR1CPB2CPB1 | |
| SCHEMBL365026 | 0.75 | CPB2 (0.45) | CPB2CPB1 | |
| SCHEMBL14523660 | 0.75 | CPB2 (0.45) | CPB2CPB1 | |
| SCHEMBL16828766 | 0.73 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1TAAR1AKR1B1CSNK2A2 | |
| SCHEMBL4832580 | 0.73 | ALPL (0.54) | ALDH1A1AKR1B1CSNK2A2CSNK2A1 | |
| Hydrochloric Acid SCHEMBL10927943 | 0.73 | NPSR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100491323-C | Biaryloxymethylarenecarboxylic acids compound | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | CN | disclosed |
| EP-1663936-B1 | BIARYLOXYMETHYLARENE-CARBOXYLIC ACIDS | HOFFMANN LA ROCHE (CH) | 2008-01-09 | — | — | EP | disclosed |
| CN-1812956-A | Biaryloxymethylarenecarboxylic acids as glycogen synthase activator | HOFFMANN LA ROCHE (CH) | 2006-08-02 | — | — | CN | disclosed |