Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671039 | 0.89 | LMNA (0.31) | LMNA | |
| SCHEMBL4673674 | 0.88 | — | — | |
| SCHEMBL4672755 | 0.88 | ALDH1A1 (0.32) | LMNA | |
| SCHEMBL4672699 | 0.86 | CYP11B1 (0.32) | LMNA | |
| SCHEMBL4672105 | 0.84 | LMNA (0.31) | LMNANPSR1 | |
| SCHEMBL4674960 | 0.84 | LMNA (0.31) | LMNANPSR1 | |
| SCHEMBL4672579 | 0.84 | ABCB1 (0.35) | — | |
| SCHEMBL4671359 | 0.82 | GPR52 (0.35) | LMNA | |
| SCHEMBL4678040 | 0.82 | CYP11B1 (0.34) | — | |
| SCHEMBL5899349 | 0.82 | CYP11B1 (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142872-B1 | AROMATIC HETEROCYCLE COMPOUNDS HAVING HIV INTEGRASE INHIBITING ACTIVITIES | SHIONOGI & CO (JP) | 2008-10-15 | — | — | EP | disclosed |
| US-6645956-B1 | 1-(5-(4-fluorobenzyl)furan-2-yl)-3-hydroxy-3-(1H-1,2,4-triazol-3 -yl)-propenone; viricides; AIDS treatment | SHIONOGI & CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-6620841-B1 | Furan or benzofuran derivatives substituted with triazole; acquired immunodeficiency syndrome (AIDS) | SHIONOGI & CO., LTD. (JP) | 2003-09-16 | — | — | US | disclosed |
| EP-1142872-A1 | AROMATIC HETEROCYCLE COMPOUNDS HAVING HIV INTEGRASE INHIBITING ACTIVITIES | SHIONOGI & CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |