Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756396 | 0.79 | NR4A2 (0.62) | PTGER4FFAR1NR4A2PPARGPPARD | |
| SCHEMBL17714039 | 0.70 | KMT2A (0.55) | PPARGNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL2760661 | 0.70 | KMT2A (0.55) | PPARGNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6661351 | 0.70 | RAB9A (0.50) | PPARGHPGDNPC1RAB9AMAPT | |
| Bicarbonate SCHEMBL9638235 | 0.70 | FFAR1 (0.71) | PTGER4FFAR1NR4A2PPARGPPARD | |
| SCHEMBL4686959 | 0.69 | PTGER4 (0.73) | PTGER4FFAR1NR4A2PPARGPPARD | |
| SCHEMBL4672078 | 0.69 | PPARD (0.50) | PTGER4FFAR1PPARGPPARDSMPD1 | |
| SCHEMBL4671564 | 0.69 | NPC1 (0.50) | PTGER4FFAR1SMPD1NPC1RAB9A | |
| SCHEMBL4693788 | 0.69 | PTGER4 (0.70) | PTGER4 | |
| Biphenyl SCHEMBL6667027 | 0.69 | KMT2A (0.53) | PPARGNPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663936-B1 | BIARYLOXYMETHYLARENE-CARBOXYLIC ACIDS | HOFFMANN LA ROCHE (CH) | 2008-01-09 | — | — | EP | claimed |