Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31651965 | 0.83 | MKNK1 (0.42) | EIF4EMKNK1MKNK2TGFBR1ALDH1A1 | |
| SCHEMBL9384191 | 0.79 | GRM5 (0.48) | RAB9AMKNK1MKNK2SMN1; SMN2TGFBR1 | |
| SCHEMBL7360342 | 0.78 | BCAT2 (0.51) | RAB9ASMN1; SMN2DHODH | |
| SCHEMBL4560363 | 0.78 | MKNK1 (0.50) | RAB9AEIF4EMKNK1MKNK2ALDH1A1 | |
| SCHEMBL946785 | 0.75 | F7 (0.47) | EIF4EMKNK1MKNK2TGFBR1ALDH1A1 | |
| SCHEMBL3100405 | 0.75 | NPC1 (0.50) | RAB9AEIF4EMKNK1MKNK2L3MBTL1 | |
| SCHEMBL17028059 | 0.73 | MKNK1 (0.50) | RAB9AEIF4EMKNK1MKNK2SMN1; SMN2 | |
| SCHEMBL27909833 | 0.73 | KDM4E (0.46) | RAB9AMKNK2SMN1; SMN2DHODHTGFBR1 | |
| SCHEMBL29356988 | 0.73 | MKNK1 (0.43) | RAB9AEIF4EMKNK1MKNK2SMN1; SMN2 | |
| SCHEMBL15903099 | 0.72 | DHODH (0.44) | RAB9ASMN1; SMN2DHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644334-B1 | ANTITHROMBOTIC ETHERS | LILLY CO ELI (US) | 2008-01-02 | — | — | EP | disclosed |