Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480845 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL1901744 | 0.78 | — | — | |
| SCHEMBL14369698 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL1903288 | 0.75 | TSHR (0.35) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL467680 | 0.68 | KCNH2 (0.38) | ALDH1A1 | |
| SCHEMBL2481612 | 0.66 | KDM4E (0.40) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL12582119 | 0.62 | MAPT (0.67) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL23980754 | 0.61 | CHRNA7 (0.44) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL18876521 | 0.61 | KDM4E (0.46) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL18876495 | 0.61 | KDM4E (0.42) | KDM4EALDH1A1MAPTPKMHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387395-A1 | AXL INHIBITORS FOR USE IN COMBINATION THERAPY FOR PREVENTING, TREATING OR MANAGING METASTATIC CANCER | Rigel Pharmaceuticals, Inc. (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8040491-B2 | Exposure method, substrate stage, exposure apparatus, and device manufacturing method | NIKON CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |