Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467582 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL12582119 | 0.65 | MAPT (0.67) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL23980754 | 0.65 | CHRNA7 (0.44) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL2480845 | 0.64 | KDM4E (0.39) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL18876495 | 0.64 | KDM4E (0.42) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL21361597 | 0.64 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL18876521 | 0.64 | KDM4E (0.46) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL13290572 | 0.64 | CHRNA7 (0.46) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL13290568 | 0.64 | CHRNA7 (0.46) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL681912 | 0.64 | CHRNA7 (0.46) | KDM4EALDH1A1MAPTPKMHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146349-A2 | CGRP RECEPTOR ANTAGONISTS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-12-21 | — | — | WO | disclosed |