Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467645 | 1.00 | TRPA1 (0.41) | TRPA1ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL467981 | 0.87 | TRPA1 (0.52) | TRPA1ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL467930 | 0.87 | TRPA1 (0.52) | TRPA1ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL467980 | 0.87 | TRPA1 (0.52) | TRPA1ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL467983 | 0.78 | TRPA1 (0.44) | TRPA1ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL467982 | 0.78 | TRPA1 (0.44) | TRPA1ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL8116733 | 0.74 | — | — | |
| SCHEMBL4299631 | 0.74 | — | — | |
| SCHEMBL4299633 | 0.74 | — | — | |
| SCHEMBL9768646 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094090-B1 | SYNERGISTIC MICROBICIDAL COMPOSITIONS INCLUDING A CYANODITHIOCARBIMATE AND A SECOND MICROBICIDE, AND METHODS OF USING THE SAME | BUCKMAN LABOR INC (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-2385759-A2 | MICROBICIDAL COMPOSITIONS INCLUDING ACTIVATED NITROGENOUS COMPOUND AND 1,4-BIS (BROMOACETOXY)-2-BUTENE, AND METHODS OF USING THE SAME | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2011-11-16 | — | — | EP | disclosed |
| US-D647205-S1 | Control unit | HU-FRIEDY MFG. CO., INC. (US) | 2011-10-18 | — | — | US | disclosed |
| US-7772156-B2 | Microbicidal compositions including a cyanodithiocarbimate and a second microbicide, and methods of using the same | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| WO-2010080305-A2 | MICROBICIDAL COMPOSITIONS INCLUDING ACTIVATED NITROGENOUS COMPOUND AND 1,4-BIS (BROMOACETOXY)-2-BUTENE, AND METHODS OF USING THE SAME | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20100173018-A1 | Microbicidal Compositions Including Activated Nitrogenous Compound and 1,4-Bis(Bromoacetoxy)-2-Butene, and Methods Of Using The Same | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2010-07-08 | — | — | US | disclosed |
| EP-2094090-A2 | SYNERGISTIC MICROBICIDAL COMPOSITIONS INCLUDING A CYANODITHIOCARBIMATE AND A SECOND MICROBICIDE, AND METHODS OF USING THE SAME | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008057817-A2 | SYNERGISTIC MICROBICIDAL COMPOSITIONS INCLUDING A CYANODITHIOCARBIMATE AND A SECOND MICROBICIDE, AND METHODS OF USING THE SAME | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20080102094-A1 | Microbicidal Compositions Including A Cyanodithiocarbimate And A Second Microbicide, And Methods of Using The Same | BUCKMAN LABORATORIES INTERNATIONAL, INC. | 2008-05-01 | — | — | US | disclosed |
| EP-0835054-B1 | EMULSIFIED COMPOSITIONS OF 1,4-BIS(BROMOACETOXY)-2-BUTENE USEFUL AS A MICROBICIDE AND PRESERVATIVE | BUCKMAN LABOR INC (US) | 2001-09-19 | — | — | EP | disclosed |
| EP-0835054-A1 | EMULSIFIED COMPOSITIONS OF 1,4-BIS(BROMOACETOXY)-2-BUTENE USEFUL AS A MICROBICIDE AND PRESERVATIVE | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1998-04-15 | — | — | EP | disclosed |
| US-5681851-A | BACTERICIDE, FUNGICIDE | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1997-10-28 | — | — | US | disclosed |
| WO-1996039828-A1 | EMULSIFIED COMPOSITIONS OF 1,4-BIS(BROMOACETOXY)-2-BUTENE USEFUL AS A MICROBICIDE AND PRESERVATIVE | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173018-A1 | Microbicidal Compositions Including Activated Nitrogenous Compound and 1,4-Bis(Bromoacetoxy)-2-Butene, and Methods Of Using The Same | BBOX1, BLVRB, MAOB | TRPA1 1596/4885ALDH1A1 514/4885CYP2C19 261/4885 |
| US-20080102094-A1 | Microbicidal Compositions Including A Cyanodithiocarbimate And A Second Microbicide, And Methods of Using The Same | TST, MYD88, AADAC | TRPA1 85/4885ALDH1A1 1047/4885CYP2C19 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.